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Pretreatment with probenecid lessens equally the natriuresis and hyperreninemia produced by Bumex. This antagonistic impact of probenecid on Bumex natriuresis just isn't because of a direct action on sodium excretion but is probably secondary to its inhibitory effect on renal tubular secretion of bumetanide. Therefore, probenecid really should not be http://bomex78778.free-blogz.com/23101580/an-unbiased-view-of

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