If a father or mother from the proband is known to possess the pathogenic variant determined in the proband, the danger to your sibs of inheriting the pathogenic variant is fifty%. As a result of minimized penetrance, sibs who inherit the pathogenic variant might or might not acquire aHUS (see https://lukastngzp.oblogation.com/31694335/the-single-best-strategy-to-use-for-ahu-s